Backed by 25 years of research & innovation

Backed by 25 years of research & innovation

We've led the way in healthy aging science, pioneering discoveries in NAD+ with Niagen®.

THE SCIENCE BEHIND NAD+

Every cell in your body is fueled by NAD+

Your 37.2 trillion cells are powered by NAD+, a vital coenzyme that fuels cellular energy and repair throughout your entire body. NAD+ levels naturally decline with age, lifestyle factors, and stressors. Replenishing NAD+ levels is essential for maintaining your cellular health, energy, and vitality.

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MEET OUR STAR SUPERNUTRIENT

The #1 NAD+ booster³

Discover Tru Niagen, a revolutionary supplement backed by decades of research and clinically proven to increase NAD+ up to 150% to keep your cells performing at their best.



Powered by Niagen®, our patented form of nicotinamide riboside, Tru Niagen is one of the most well-researched, efficient, and superior NAD+ precursors available, ensuring you get the best for your health.

Whole-body benefits

From your daily routine to your most challenging goals, Tru Niagen powers your cellular health, helping you thrive at every age.

  • Healthy Aging¹

    Boost NAD+ levels for energized, resilient cells, ready for repair at any time.

  • Brain¹

    Power your hardworking brain cells withincreased cellular energy.

  • Heart¹†

    Support your heart cells with the essential care they need for cellular resilience.

  • Muscle¹

    Energize muscle cells to help fuel muscle recovery and repair.

  • Cellular Health¹

    Support your 37.2 trillion cells with increased NAD+ for energy and repair.

  • Lifestyle Stress Management*‡

    Help counter the impact of physiological stress on your cells that further deplete NAD+.

    Backed by world-leading researchers

    "Niagen, Niagen Bioscience’s patented nicotinamide riboside product, is one of the most well-studied, carefully controlled dietary supplements, and indeed, a gold standard in the industry."

    Roger Kornberg, Ph.
    D.Nobel Prize Winner in Chemistry | Mrs. George A. Winzer Professor of Medicine, Stanford | Niagen Bioscience Scientific Advisory Board Chairman

    "Disturbances in NAD coenzymes can leave tissues unable to repair themselves, generate energy, and perform their normal homeostatic functions. In many conditions of metabolic stress, the genes that convert NR to NAD are up-regulated, which provides unique value over all other NAD precursors."

    Charles Brenner, Ph.D.
    Alfred E Mann Family Foundation Chair in Diabetes and Cancer Metabolism at City of Hope National Medical Center | Niagen Bioscience Chief Scientific Advisor

    "With the clear preclinical benefits of NR observed in the brains of mice, I look forward to future clinical trial findings from testing in human subjects. In the meantime, the known ability of NR to enhance mitochondrial function and cellular energy makes it a top choice for my personal daily regimen."

    Dr. Rudolph Tanzi
    Kennedy Professor of Neurology, Harvard University | Director, Genetics and Aging Research Unit, Massachusetts General Hospital Niagen Bioscience Scientific Advisory Board Member

    "Tru Niagen stands out as the leading, gold-standard NAD+ supplement... crucial for maintaining cellular resilience, energy metabolism, and overall cellular repair. Further, it features patented nicotinamide riboside (NR), which is the most efficient NAD+ precursor available."

    Dr. Jim LaValle
    Clinical Pharmacist | CEO of Metabolic Code Enterprises | Former Niagen Bioscience Consultant

    Frequently Asked Questions

    What is NAD+ and how does it work?

    NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.

    What are the potential benefits of taking NAD+ supplements?

    NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.

    What is the difference between Tru Niagen and other NAD brands on the market?

    Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 35+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels. 

    This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically proven to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs. 

    How quickly can I expect to see results from taking Tru Niagen?

    Most people report noticing improvements in cellular energy and overall wellbeing within 2-4 weeks of consistent daily use. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.  

    Clinical studies show that Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine. 

    Is Tru Niagen safe, and are there any side effects?

    Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.  

    Niagen is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.² Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded. 

    In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.